No. No. 24 Missouri is not expected to start quarterback Brady Cook against visiting Oklahoma on Saturday night, sources told ESPN on Friday.

Cook is dealing with both an ankle and wrist injury, having left Missouri’s past two games while dealing with injuries.

The missed game for Cook would end a streak of 35 consecutive starts, including every game of the 2024, 2023 and 2022 seasons.

Veteran backup Drew Pyne will start in place of Cook. He is 8-3 in his career as a starter, which includes his time at Notre Dame and Arizona State.

Pyne struggled in place of Cook at Alabama in Missouri’s final game, throwing three interceptions while completing six of 12 passes for 42 yards. In Cook’s place against Auburn, Pyne completed 10 of 21 passes for 78 yards.

Cook has thrown for 1,575 yards and seven touchdowns this year. In his career, he has thrown for 8,048 yards and 45 touchdowns.

He played valiantly in a comeback win over Auburn, returning from the hospital to lead a second-half comeback.

The news of Cook’s absence is somewhat mitigated by the return of starting tailback Nate Noel, sources said. He missed the Alabama game due to a foot injury. Noel rushed for 503 yards this season and is averaging 5.9 yards per carry.

247Sports.com first reported that Cook would sit out Saturday’s game.