GLENDALE, Ariz. – Kyler Murray did it again.

The Arizona Cardinals quarterback turned and burned against the Los Angeles Chargers on Monday night, breaking free for a 44-yard touchdown run in the fourth quarter that brought back memories of his 50-yard touchdown run in San Francisco two weeks ago. The run put the Cardinals ahead 14-9 early in the fourth quarter, a lead that was ultimately lost on Chargers kicker Cameron Dicker’s leg, 15-14. But Murray’s ability to guide Arizona’s offense on a winning drive, control the clock and put his offense in good position led Cardinals to a 17-15 victory on a 32-yard field goal by kicker Chad Ryland during the final action.

The win moved Arizona into a tie for second place in the NFC West, with a trip to Miami scheduled this weekend. The win also helped Arizona redeem itself after an embarrassing loss in Green Bay last week.

But it was Murray’s run that led to the sudden resurgence.

According to ESPN Research, he became the fourth quarterback since the merger with multiple touchdown runs of 40 or more yards. He joined Justin Fields in 2022, Michael Vick in 2002 and Steve McNair in 1998.

Most surprising achievement: The Cardinals defense allowed Justin Herbert to throw for 349 yards, but it prevented him from throwing a touchdown pass. Arizona had two huge stops on third down, one by rookie cornerback Max Melton and another by second-year defenseman Garrett Williams. Both helped hold the Chargers to four field goals. The Cardinals’ pass rush was able to get to Herbert seven times for three sacks.

Troubling trend: Cardinals rookie receiver Marvin Harrison Jr. finished with 21 yards on three catches, extending his streak of no 100 yards in a game to five. His catches came in the first, second and fourth quarters, continuing the trend of Harrison disappearing for entire quarters or more. His six goals on Monday night were the third fewest in a game this season.

QB breakdown: Murray didn’t have a dazzling game, throwing for 145 yards, a touchdown and an interception on 14-for-26 passing, but he made the plays when he needed to, like the touchdown run. And he controlled the offense while rushing to buy time when necessary. — Josh Weinfuss

Next game: at Miami Dolphins (1 p.m. ET, Sunday)

Quarterback Justin Herbert looked like himself again, throwing for 349 yards and picking off the Cardinals’ defense with ease. And yet it wasn’t enough for the Chargers.

Their defense, which had been one of the best against the run all season, faltered, allowing the Cardinals to rush for 178 yards, including a 44-yard run by Murray in the fourth quarter for a touchdown.

The Chargers never found the end zone Monday night, relying on Dicker for five field goals. Their offense, which dominated teams on the field early in the season, is no longer dominant and the team hasn’t scored in the fourth quarter since Week 1. It will be another week full of questions for this team and offensive coordinator Greg Roman about how to fix the offense and whether any upgrades are needed at receiver.

Forecast for next week: Ladd McConkey has the first 100-yard receiving game after struggling on Monday. The Chargers will play the New Orleans Saints in Week 8, who have given up the seventh-most passing yards in the NFL over the past three games. It could be a breakout game for McConkey, who had five catches for 45 yards on Monday. Herbert has described McConkey as one of his favorite targets.

Promising/worrying trend: Herbert has been sacked multiple times in the last four games. Herbert has spent much of the time navigating collapsing sacks and throws while a defensive lineman was draped around his waist or other body parts. He was sacked three times on Monday, the fourth game in a row that the opponent has sacked him multiple times. It’s a concerning statistic for an offensive line with three first-round picks: left guard Zion Johnson, right tackle Joe Alt and left tackle Rashawn Slater.

Eye-popping statistic: According to Elias Sports Bureau, Herbert is the fastest player in NFL history with 1,700 completions. In a season where Herbert had low points in almost every category, he looked like the Herbert of old and set another record. The only player to reach 1,700 completions in fewer than 70 games is Kansas City Chiefs quarterback Patrick Mahomes, who did so in 69 games. Herbert’s 1,700th career completion came to Will Dissly at the 2:20 mark of the second quarter. — Kris Rhim

Next game: vs. New Orleans Saints (4:05 PM ET, Sunday)