The 49ers have ruled out quarterback Brock Purdy for Sunday’s game against the Packers.

It seemed to be a trend at the time Purdy was not on the field before the start of Friday training.

Purdy has a right shoulder injury that kept him from throwing the ball Wednesday and Thursday, which was a surprise to the team. He was listed as limited the first two days of practice before not practicing Friday.

“I don’t want to say there are any long-term concerns,” coach Kyle Shanahan said Friday. “You know, he got the MRI on Monday and thought he just needed some rest and really wasn’t worried about him not being well this week. But when he started on Thursday, he surprised him, surprised us how it felt, so we had to shut him down. So I really don’t know what to think about it. The MRI doesn’t look like much, but the way he responded this week is really up in the air for next week. We’ll have to see that on Monday.”

Brandon Allen will start this week, with Joshua Dobbs as his backup. Allen hasn’t started a game since 2021 and has played just 16 games in his career, including nine starts.

Purdy appeared to injure the shoulder when his hand struck the arm of Seahawks cornerback Devon Witherspoon as he released a pass early in the fourth quarter on Sunday, although Shanahan said Purdy doesn’t know when he was injured. Purdy missed no time in Sunday’s loss due to the injury.

“I was just complaining about how tight it was the whole game,” Shanahan said. “It actually happened the whole game. That’s why he was warming up a lot more than usual. He said he had a hard time keeping it loose. After the game it really started to hurt, so we did an MRI for it on Monday morning.”

Purdy has thrown for 2,613 yards with 13 touchdowns and eight interceptions this season.

The 49ers also ruled out Nick Bosa (hip/oblique) on defense, adding another concern as they face what feels like a must-win game in Green Bay.

Cornerback Charvarius Ward (personal), punt returner Jacob Cowing (concussion), linebacker Tatum Bethune (knee) and defensive tackle Kevin Givens (groin) also will not play this week.

Left tackle Trent Williams (ankle) and center/guard Jon Feliciano (knee) are questionable. Williams did not train this week.