This week sees the CONMEBOL World Cup qualifiers take place and one of the highlights of this final round of matches will be the match between Argentina and Chile at the Estadio Monumental in Buenos Aires.

The reigning world champions and the South American champions are the big favorites to win, according to the bookmakers. The last time these teams met, they were also winners. Lautaro Martinez scored the winning goal in the final phase of the group stage of the Copa America, which was won 1-0.

Lionel Scaloni’s side sit comfortably at the top of the CONMEBOL standings, with five wins from their opening six games, putting them in a strong position to qualify for the 2026 World Cup in the United States, Mexico and Canada. Chile, meanwhile, face a battle to join them in the expanded finals, having collected just five points from six games. Only Bolivia and Peru sit below them in the 10-team table.

Sporting News takes a look at the latest odds and predictions for this match.

MORE: A Complete Guide to Betting on Soccer in the United States

Argentina vs Chile Prediction, Odds

• Moneyline-lean: Argentina (-275)
• Score prediction: Argentina 2-0 Chile

Even without Lionel Messi, Argentina are the obvious favorites to beat a struggling Chilean side. With that in mind, it makes sense to add several squads to find more attractive opportunities.

If Argentina wins 0-0, the odds at BetMGM are -105. That’s a better option than simply betting on a home win.

Similarly, it can be worthwhile to bet on a low-scoring match: the Albiceleste have failed to score more than once in their last two home games against Chile in World Cup qualifying, and they also failed to score in their most recent Copa America clash.

Facts about the match Argentina vs. Chile

• Date: Thursday, September 5, 2024
• Kick-off time: 9:00 PM local time (8:00 PM ET / 5:00 PM PT)
• Location: Estadio Mas Monumental (Buenos Aires, Argentina)
• Referee: To be determined
• Last meeting: Argentina 1-0 Chile (June 25, 2024 | Copa America)

Argentina vs Chile Best Bet

• Choice: Argentina wins and Chile fails to score
• Chances: -105 (BetMGM)

Argentina have conceded just one goal in the Copa America — in a 1-1 quarter-final draw with Ecuador — and have won each of their other six matches. In World Cup qualifying, too, all five of their victories so far have come without their opponents conceding a goal.

Chile, meanwhile, have scored just three times in 2026 World Cup qualifiers and failed to find the net once in the Copa America. This feels like an easy choice.

Argentina vs Chile live stream, tv channel