In a season where injuries have been rampant, fantasy managers saw another top player go down on Thursday night. This time, 49ers running back Jordan Mason suffered a shoulder injury in the second quarter of a win over the Seahawks. He tried to return in the third quarter, but he only had one rushing attempt before heading back to the sideline.

Mason did not return to the game.

49ers coach Kyle Shanahan did not provide any information on Mason after the game, but suggested more information on his status will come Friday.

“I don’t know, you never know,” Shanahan said. “I mean, the adrenaline is a little different during games these days. We’ll know more tomorrow.”

Mason entered last night’s game as one of the best running backs in fantasy football and an absolute gift from the fantasy gods. After all, he replaced the best running back in fantasy football, Chrisitan McCaffrey, who hasn’t played yet this season due to Achilles tendon issues and has performed tremendously.

The 49ers have a bye in Week 9, so it’s possible Mason misses the next two weeks and returns in Week 10. But here’s the problem… reports suggest McCaffrey could be back after the bye as well. SI NFL Insider Albert Breer told Charissa Thompson before Thursday’s game that McCaffrey “started feeling like himself again last week” and that the 49ers will look to step him up “in the last few days.”

So, worst case scenario for Mason, he could come back as a backup at CMC.

In the meantime, fantasy managers should file a waiver claim for Isaac Guerendo. He was solid in Mason’s absence, rushing 10 times for 99 yards (9.9 YPC) and just missing scoring a touchdown. If Mason were out for the next two weeks, Guerendo would be a solid RB2.