50 Cent took on Sean “Diddy” Combs after his longtime rival was arrested Monday night on sex trafficking and racketeering charges.

The 49-year-old “In da Club” rapper posted a photo to Instagram from his appearance on “The Drew Barrymore Show” and joked about the $1,000 bottles of lubricant and baby oil that were seized from Combs’ home by Homeland Security in March.

“Here I am in good company with @thedrewbarrymoreshow,” 50 Cent’s caption began, alongside a photo of himself and Barrymore, 49.

“And I don’t have 1,000 bottles of lube in the house,” he added.

50 Cent has been harassing Combs, 54, over the past year over his numerous legal troubles.

In July, before Combs was arrested, 50 Cent gave an interview to the Hollywood Reporter in which he explained that he never went to the mogul’s parties because he felt like “there was just an uncomfortable energy to it.”

The “Power” producer and actor — who is making a documentary for Netflix about the sexual assault allegations against Combs — also clarified that he has never been friends with him, despite their history of working together.

“It was mostly work. I wouldn’t call it a friendship because there wouldn’t be any disappointment between us if we weren’t talking,” 50 Cent said. “There were times when we worked together. Jennifer Lopez even told him that he should work with me as a songwriter in the beginning. And I was there in the beginning stages, and he could have gotten me my record deal at that point.”

When asked why other celebrities haven’t spoken out about Diddy, 50 Cent said, “Some of them were involved, were at the parties, had a great time, so they don’t know what’s on the tape and what’s not, so they’re not going to say anything because maybe they had too much fun.”

Combs was arrested Monday night at the Park Hyatt New York in Manhattan.

The record executive faces three federal charges including racketeering, conspiracy, human trafficking and transportation for the purpose of prostitution.

The 14-page, unsealed indictment alleged that Combs lured female victims and male sex workers into drug-fueled, often days-long, sexual performances dubbed “Freak Offs.”

The women, often brought in under the pretense of a romantic relationship, were then pumped full of drugs in an attempt to keep them “obedient and compliant,” court documents said.

The indictment also alleges that federal authorities found 1,000 bottles of lubricant and baby oil, as well as three AR-15s, when they raided Combs’ homes in Miami and Los Angeles in March.

The bottles were allegedly used in the “Freak Offs,” during which Combs allegedly “punched, kicked, threw objects at, and sometimes dragged victims by their hair,” the complaint said.

He allegedly threatened the careers and livelihoods of victims if they refused to participate in the Freak Offs.

After Diddy’s arrest, his attorney said in a statement: “We are disappointed with the decision to prosecute Mr. Combs, which we believe is an unfair one, by the United States Attorney’s Office.

“He is an imperfect person, but not a criminal. To his credit, Mr. Combs has been nothing but cooperative with this investigation and voluntarily relocated to New York last week in anticipation of these charges.”

Combs has faced a series of lawsuits over the past year from people who allege he physically and sexually abused them during his famed producing days in the 1990s and 2000s.