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    • Predictions, how to watch TNF
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    Predictions, how to watch TNF

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    Week 6 of the 2024 NFL season kicks off on “Thursday Night Football” with a huge NFC West clash as the San Francisco 49ers (2-3) travel to take on the Seattle Seahawks (3-2).

    Both teams are coming off disappointing losses in Week 5 and will be eager to get back in the win column during prime time at Lumen Field in Seattle. Both teams had a seven-point lead at home and were upset on Sunday.

    The Seahawks have lost two straight games after an impressive 3-0 start to the season under first-year head coach Mike Macdonald. Seattle was upset 29-20 by the New York Giants on Sunday.

    The defending NFC champion 49ers are coming off a 24-23 loss at home to the Arizona Cardinals. It’s been a tumultuous start to the season for San Francisco. Running back Christian McCaffrey remains sidelined. The 49ers have a Super Bowl rematch against the Kansas City Chiefs in Week 7, but they can’t afford to overlook their division rivals Thursday night.

    As of Week 6, both teams rank in the top ten in total offense (SF 2nd, 407.4 YDS/G) and (SEA 7th, 376.2 YDS/G). There is plenty of star power on both rosters, adding to the excitement of this matchup.

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    USA TODAY Sports provides highlights, analysis and more from the Week 6 “Thursday Night Football” matchup between the Seahawks and 49ers.

    • Date: Thursday October 10, 2024
    • Time: 8:15 PM ET

    The Seahawks-49ers matchup kicks off Week 6 of the 2024 NFL season with “Thursday Night Football” at 8:15 PM ET.

    • Live stream: Amazon Prime Video

    “Thursday Night Football” streams exclusively on Amazon Prime Video.

    Al Michaels (play-by-play) and Kirk Herbstreit (analyst) will be in the broadcast booth for Prime Video, while Kaylee Hartung (sideline) and Terry McAulay (rules analyst) will provide additional coverage.

    The Prime Video pregame, halftime and postgame shows feature Charissa Thompson as host, as well as former NFL players Ryan Fitzpatrick, Tony Gonzalez, Richard Sherman and Andrew Whitworth as analysts. Taylor Rooks is the lead reporter for Prime Video’s “Thursday Night Football” coverage.

    Watch “Thursday Night Football” with a Prime Video subscription

    Here are the USA TODAY Sports staff’s predictions for the “Thursday Night Football” Week 6 matchup:

    • Lorenzo Reyes: 49ers 25, Seahawks 17
    • Tyler Dragon: 49ers 25, Seahawks 20
    • Jordan Mendoza: 49ers 26, Seahawks 20

    Inactive 49ers players:

    • QB Joshua Dobbs
    • TE Brayden Willis
    • CB Charvarius district
    • LB Demetrius Flannigan-Fowles
    • OL Ben Barch
    • KJake Moody
    • DT Jordan Elliott

    Inactive Seahawks players:

    • CB Riq Wol
    • LB Trevis Gipson
    • C Olu Oluwatimi
    • OG Sataoa Laumea
    • WR Dareke Young
    • DT Byron Murphy II
    • DE Myles Adams

    The 49ers are the favorites to beat the Seahawks in Week 6, according to BetMGM NFL odds. Do you want to bet? Check out the best mobile sports betting apps offering NFL betting promotions in 2024, including the ESPN BET app and Fanatics Sportsbook promo code.

    • Spread: 49ers (-3.5)
    • Moneyline: 49ers (-190); Seahawks (+155)
    • Top/bottom: 49

    Not interested in this game? In our guide to NFL betting, picks and spreads, you’ll find the odds for ‘Sunday Night Football’ and ‘Monday Night Football’.

    New to sports betting? USA TODAY readers can claim exclusive promotions and bonus codes at the top online sportsbooks and sports betting sites.

    FEELING HAPPY? Here are the best parlay bets and odds for this week’s NFL games

    It will be a slightly cold but clear night in Seattle with a high of 58 degrees at kickoff and a low of 51 degrees at midnight. According to the Weather Channel, winds will reach a maximum of 8 miles per hour, while the chance of precipitation during the game will be less than 10%.

    The Seahawks enter the Week 6 “TNF” showdown in sole possession of first place in the NFC West. However, with a win tonight, San Francisco can move to a tie.

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