Portland Trail Blazers guard Matisse Thybulle will miss three to four weeks after undergoing a procedure to address inflammation in his right knee, the team announced ahead of Friday night’s final game against the Utah Jazz in Moda Center.

The Blazers start the season without two of their regular shooting guards. Shaedon Sharpe will miss the first few weeks of the season due to a posterior labral tear in the left shoulder.

“I don’t like it at all,” Blazers coach Chauncey Billups said of the loss of both guards. ‘But you do what you have to do. But obviously those two guys were a big part of our rotation and what we want to do. But we will survive.”

The Blazers open the regular season at home against the Golden State Warriors on Wednesday evening.

Guard Anfernee Simons, who missed the first three preseason games due to right ankle soreness, returns to the starting lineup against the Jazz.

Billups announced he would start Simons, Deni Avdija, Toumani Camara, Jerami Grant and rookie center Donovan Clingan.

Scoot Henderson comes off the bench.

Jabari Walker (ankle pain) remains ruled out. Deandre Ayton will sit down to rest.

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PORTLAND TRAILBLAZERS VS. UTAH JAZZ

What: Trail Blazers (2-1) vs. Jazz (4-1), 7 p.m., Friday.

Where: Moda Center

Radio: Rip City Radio (KPOJ 620 AM).

TV channel: KATU (antenna: 2.2 in Portland).

Streaming: BlazerVision.

CHANCES (Oregon Lottery/DraftKings)

Moneyline: POR-108 | UTA-112

Spread: POR-1 | Top/Bottom: 220

INJURIES

Wind players: Jabari Walker (ankle pain), Shaedon Sharpe (posterior labral tear in the left shoulder), Robert Williams III (left hamstring strain), Matisse Thybulle (pain in the right knee) and Deandre Ayton (rest) are out.

Jazz: Isaiah Collier (right hamstring injury) is out.

NEXT

The Blazers open the regular season against the Golden State Warriors at the Moda Center on Wednesday at 7 p.m.