The Philadelphia 76ers fell to the LA Clippers on Wednesday night and now turn their attention to the Los Angeles Lakers in hopes of securing their second win of the season. This game marks the second of three games that Joel Embiid will sit out due to his suspension. With Tyrese Maxey also nursing a hamstring issue and set to miss time, the Sixers may be without two-thirds of their Big 3 for this game.

So far, the Sixers have disappointed dramatically — even by their standards without Embiid. The offense has often been stagnant and the rotation is a work in progress, with several players having drastic minute fluctuations. Assuming things don’t go well for Maxey, guys like Kyle Lowry, Jared McCain and even Reggie Jackson will have to step up.

Outside of the guard game, this will likely be another game where they rely heavily on Andre Drummond and Guerschon Yabusele. Anthony Davis didn’t play for the Lakers’ last game due to an ankle injury, but if he does (he’s considered likely), Drummond will see significant playing time. If Davis doesn’t play, the Sixers could return to Yabusele, who posted a season-low 10 minutes in the final game against the Clippers. Outside of Davis, the Lakers don’t have much depth on the court, with guys like Rui Hachimura and Jaxson Hayes being their only options.

On the other side of the court, the Los Angeles Lakers have been solid under their new head coach, JJ Redick. They boast a top-10 offense so far on the season, although their defense is lagging and ranks just 28th in the league. By comparison, the Sixers rank 26th in offensive rating and 22nd in defense. Not ideal!

This game, much like the Clippers’ game, has the potential to move the team in the right direction. They have two more games without Embiid against the Lakers and Charlotte Hornets. Both could be won if Paul George returns to form, although the showdown with Davis and LeBron James will be daunting. Two wins would bring their season record to 3-6, an early season gap, but not a deep one.

Can the Sixers get their first win of November without some of their big names? Let’s find out.

Game details

WHO: Philadelphia 76ers at Los Angeles Lakers
When: 10:00 PM ET
Where: Cyrpto.com Arena, Los Angeles, CA
Watch: NBC Sports Philadelphia, ESPN
Radio: 97.5 The fanatic
To follow: @LibertyBallers