The No. 2 Oregon Ducks have a nearly 30-point lead in their Friday night game against Purdue in West Lafayette, Indiana.

Will Oregon cover the spread, or will the Boilermakers make it a week after forcing Illinois into overtime?

• WATCH: Stream most of this week’s best college football games live for FREE with Fubo (free trial) or with DirectTV stream (free trial).

Meanwhile, an injury-ravaged Oregon State team plays host to the UNLV Rebels on Saturday night. Can the Beavers, who are 6.5-point underdogs, win at home?

Elsewhere in the Big Ten this week, Michigan travels to Illinois for a top-25 matchup and one-loss Nebraska visits undefeated Indiana.

Get this week’s college football odds, plus score predictions for select games from The Oregonian/OregonLive’s college football coverage team.

No. 2 Oregon (6-0, 3-0) at Purdue (1-5, 0-3)

Game details: 5:00 PM PT Friday at Ross-Ade Stadium in West Lafayette, Indiana

TV channel and live stream: Fox and Fox Sports Live

Last line: Oregon by 29.5

Top/bottom: 60.5

Predictions

Ryan Clarke: Oregon 38, Purdue 7

James Crepea: Oregon 42, Purdue 14

Nick Daschel: Oregon 42, Purdue 31

Aaron Fentress: Oregon 44, Purdue 17

Joe Freeman: Oregon 50, Purdue 13

Sean Meagher: Oregon 48, Purdue 17

Joel Odom: Oregon 45, Purdue 10

Bill Oram: Oregon 42, Purdue 17

UNLV (5-1) at Oregon State (4-2)

Game details: 7pm PT Saturday at Reser Stadium in Corvallis

TV channel and live stream: The CW

Last line: UNLV with 6.5

Top/bottom: 59.5

Predictions

Ryan Clarke: UNLV 30, Oregon State 20

James Crepea: UNLV 42, Oregon State 28

Nick Daschel: UNLV 45, Oregon State 35

Aaron Fentress: UNLV 29, Oregon State 26

Joe Freeman: UNLV 33, Oregon State 30

Sean Meagher: UNLV 35, Oregon State 31

Joel Odom: UNLV 44, Oregon State 34

Bill Oram: UNLV 38, OSU 17

Nebraska (5-1, 2-1) and Indiana (6-0, 3-0)

Game details: 9 a.m. PT Saturday at Memorial Stadium in Bloomington, Indiana

TV channel and live stream: Fox and Fox Sports Live

Last line: Indiana with 6.5

Top/bottom: 49.5

Predictions

Ryan Clarke: Indiana 31, Nebraska 24

James Crepea: Indiana 35, Nebraska 31

Nick Daschel: Indiana 32, Nebraska 28

Aaron Fentress: Nebraska 32, Indiana 30

Joe Freeman: Indiana 25, Nebraska 20

Sean Meagher: Indiana 38, Nebraska 24

Joel Odom: Indiana 34, Nebraska 30

Bill Oram: Indiana 27, Nebraska 21

Wisconsin (4-2, 2-1) and Northwestern (3-3, 1-2)

Game details: 9 a.m. PT Saturday at Lanny and Sharon Martin Stadium in Evanston, Illinois

TV channel and live stream: Big Ten Network and Fox Sports Live

Last line: Wisconsin with 7.5

Top/bottom: 41.5

Predictions

Ryan Clarke: Wisconsin 30, Northwest 27

James Crepea: Wisconsin 24, Northwest 21

Nick Daschel: Northwest 20, Wisconsin 17

Aaron Fentress: Wisconsin 27, Northwest 23

Joe Freeman: Wisconsin 23, Northwest 14

Sean Meagher: Wisconsin 27, Northwest 20

Joel Odom: Wisconsin 30, Northwest 17

Bill Oram: Northwest 21, Wisconsin 15

UCLA (1-5, 0-4) at Rutgers (4-2, 1-2)

Game details: 9 a.m. PT Saturday at SHI Stadium in Piscataway, New Jersey

TV channel and live stream: FS1 and Fox Sports Live

Last line: Rutgers with 5

Top/bottom: 40.5

Predictions

Ryan Clarke: Rutgers 20, UCLA 17

James Crepea: Rutgers 42, UCLA 21

Nick Daschel: Rutgers 28, UCLA 20

Aaron Fentress: Rutgers 23, UCLA 17

Joe Freeman: Rutgers 24, UCLA 17

Sean Meagher: Rutgers 37, UCLA 10

Joel Odom: Rutgers 31, UCLA 21

Bill Oram: Rutgers 33, UCLA 13

No. 24 Michigan (4-2, 2-1) and No. 22 Illinois (5-1, 2-1)

Game details: 12:30 PM PT Saturday at Memorial Stadium in Champaign, Illinois

TV channel and live stream: CBS and Paramount+

Last line: Michigan with 3.5

Top/bottom: 44.5

Predictions

Ryan Clarke: Michigan 27, Illinois 24

James Crepea: Illinois 28, Michigan 24

Nick Daschel: Illinois 21, Michigan 20

Aaron Fentress: Illinois 26, Michigan 23

Joe Freeman: Michigan 24, Illinois 20

Sean Meagher: Illinois 24, Michigan 21

Joel Odom: Michigan 27, Illinois 24

Bill Oram: Michigan 38, Illinois 35

Hawaii (2-4) at Washington State (5-1)

Game details: 12:30 PM PT Saturday at Martin Stadium in Pullman, Washington

TV channel and live stream: The CW

Last line: Washington State by 18.5

Top/bottom: 55.5

Predictions

Ryan Clarke: Washington State 41, Hawaii 14

James Crepea: Washington State 42, Hawaii 21

Nick Daschel: Washington State 24, Hawaii 7

Aaron Fentress: Washington State 37, Hawaii 27

Joe Freeman: Washington State 42, Hawaii 20

Sean Meagher: Washington State 42, Hawaii 21

Joel Odom: Washington State 41, Hawaii 17

Bill Oram: Washington State 49, Hawaii 6

USC (3-3, 1-3) at Maryland (3-3, 0-3)

Game details: 1:00 PM PT Saturday at SECU Stadium in College Park, Maryland

TV channel and live stream: FS1 and Fox Sports Live

Last line: USC with 7.5

Top/bottom: 56.5

Predictions

Ryan Clarke: USC 30, Maryland 10

James Crepea: USC 42, Maryland 21

Nick Daschel: USC 38, Maryland 20

Aaron Fentress: USC 31, Maryland 24

Joe Freeman: USC 33, Maryland 24

Sean Meagher: Maryland 28, USC 24

Joel Odom: USC 34, Maryland 14

Bill Oram: Maryland 28, USC 21